Testing in progress at green uptrend support line.
Support failure will result in further price drop to gap support at $2.
Bulls and bears almost matching each other at every level except at the highest and most important level.
Being one of Vietnam's only two national hi-tech parks and considered one of Ho Chi Minh City's five focal economic projects serving as the driving force for the city's development until 2010, Saigon Hi-Tech Park (SHTP) has received exceptional supports from both the central and local governments, as well as from other relevant state agencies. As a result, the Park has been authorized to offer the highest tax incentives and one-stop investment application service to investors.
At the same time, the Park has a number of advantages, such as close proximity to many educational institutions, airports, and seaports and close connection with local universities, while its dedicated and experienced stall creates an environment conducive to tenants operating successfully. SHIP also offers a "one-stop-shop" application service and highest tax incentives allowed by the law to help investors conduct their businesses.
SHIT' is focusing on calling for investment in four sectors of priority: (1) micro electronics, information technology and telecommunications, (2) precision mechanics and automation. (3) Biotechnology applied in agriculture, pharmaceuticals and the environment, and (4) nanotechnology, and new and advanced materials.Investment in SHTP can be in multiple forms, be it high-tech manufacturing, high-tech services (call centers, data centers, software development), research and development, incubation or training.
Following its inception in late 2002, Saigon Hi-Tech Park has granted investment licenses to 25 projects with total committed capital of $1,366 billion. Key tenants include Intel Corporation (US), Jabil Corporation (US), Nidec Corporation (Japan), Sonion A/S (Denmark) and FPT (Vietnam).
http://www.shtp.hochiminhcity.gov.vn/webshtp/news/content.aspx?cat_id=512
Somatic cell nuclear transfer (SCNT), also known as "therapeutic cloning", is an intensive area of study for stem cell scientists. It potentially provides a way to make patient-tailored embryonic stem (ES) cell lines to avoid the problem of immune rejection of cells transplanted for therapy
It has long been believed in the cloning field that successful SCNT requires the use of unfertilised eggs. Eggan and colleagues at Harvard University now publish a remarkable technique that proves that unfertilised eggs are not required, at least not in mice1. They show that very early embryos can be used as recipient cytoplasts for nuclear transplantation, allowing the production of cloned animals and somatic cell–derived ES cell lines similar to those needed for patient-tailored ES cell therapies.
The procurement of human oocytes is a thorny issue because of the invasiveness of the procedure to retrieve them from women's ovaries. The authors argue that it will be easier to obtain early human embryos from in vitro fertilization (IVF) clinics than unfertilised oocytes, thus overcoming one of the major logistic and ethical hurdles of SCNT. Early embryos are destroyed in the process, but they would be ones donated by couples who had excess embryos following IVF.
http://www.nature.com/stemcells/2007/0706/070607/full/stemcells.2007.30.html
Proliferation without differentiation
The ability of stem cells to self-renew depends, among other things, on their ability to divide. However, the typical mechanism that controls cellular proliferation — the G1 checkpoint — is associated with differentiation in stem cells. How can stem cells proliferate without losing multipotency? Reporting in Nature, Patrik Ernfors of the Karolinska Institutet in Sweden and colleagues show that proliferation is controlled in some stem cells during the DNA synthesis phase, or S phase, rather than during the G1 phase.
The authors initially observed that embryonic stem (ES) cells possess functional -aminobutyric acid A receptors (GABAARs), Treating these cells with the GABAAR-specific agonist muscimol reduced the number of stem cells in culture by causing the accumulation of cells in S phase (and thereby preventing cells from undergoing cell division). While fewer in number, treated cells could differentiate normally.
Further analysis revealed that this GABAAR signalling affects proliferation only if histone H2AX, a component of the S/G2 DNA-damage checkpoint, can be phosphorylated by PIKK kinases. Intriguingly, and unlike other cases that involve this checkpoint, GABAAR-mediated H2AX phosphorylation does not require DNA damage.
The authors also showed that knocking out a crucial GABAAR subunit makes blastocyst-stage mouse embryos develop more rapidly. That is, decreased GABAAR signalling results in faster ES cell proliferation.
These results provide the first mechanism by which stem cells can control proliferation independently from multipotency. The authors not only demonstrate that this mechanism controls division in cultured and mouse blastocyst ES cells, they also show that it functions in neural crest stem cells. Thus, GABAAR signalling may represent a homeostatic control for stem cell numbers, such that fewer stem cells are produced at high levels of signalling. If this is the case, this pathway could be used to regulate the number of stem cells in adult stem cell niches, with potential applications for neurological diseases and cancer. Further work, however, is needed to determine whether this pathway is conserved in other types of stem cells.
http://www.nature.com/stemcells/2008/0801/080124/full/stemcells.2008.28.html
